Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM2B | Q8NHM5 | 14/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.48 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27584327 | 0.98 | CHRM5 (0.52) | KDM2BKDM4EMAPK1CHRM5ADRA2C | |
| SCHEMBL27584353 | 0.96 | KDM2B (0.52) | KDM2BALDH1A1 | |
| SCHEMBL21047314 | 0.95 | KDM2B (0.57) | KDM2B | |
| SCHEMBL13905846 | 0.85 | SMN1; SMN2 (0.47) | KDM2BKDM4EMAPK1CHRM5ADRA2C | |
| SCHEMBL13905729 | 0.83 | SMN1; SMN2 (0.50) | KDM2BKDM4EMAPK1CHRM5ADRA2C | |
| SCHEMBL17873962 | 0.81 | SMN1; SMN2 (0.43) | KDM2BCHRM5ADRA2C | |
| SCHEMBL28941581 | 0.79 | CHRM5 (0.48) | KDM2BKDM4EMAPK1CHRM5ADRA2C | |
| SCHEMBL740141 | 0.78 | SMN1; SMN2 (0.54) | KDM2BALDH1A1 | |
| SCHEMBL771607 | 0.78 | SMN1; SMN2 (0.54) | KDM2BALDH1A1 | |
| SCHEMBL1609328 | 0.78 | SMN1; SMN2 (0.54) | KDM2BALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1374959-A | Piperidine quinolyl propyl derivatives, preparation method and compositions containing same | AVENTIS PHARMA SA (FR) | 2002-10-16 | — | — | CN | disclosed |