Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.48 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.48 |
| ▸ | GBA1 | P04062 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | KDM2B | Q8NHM5 | 5/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | CCR1 | P32246 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13905846 | 0.98 | SMN1; SMN2 (0.47) | SMN1; SMN2CHRM5ADRA2CGBA1ACHE | |
| SCHEMBL17873962 | 0.94 | SMN1; SMN2 (0.43) | SMN1; SMN2CHRM5ADRA2CGBA1KDM2B | |
| SCHEMBL4678458 | 0.90 | PLG (0.45) | SMN1; SMN2KDM2B | |
| SCHEMBL27584327 | 0.85 | CHRM5 (0.52) | SMN1; SMN2CHRM5ADRA2CKDM4EMAPK1 | |
| SCHEMBL27564353 | 0.83 | KDM2B (0.52) | CHRM5ADRA2CKDM4EMAPK1KDM2B | |
| SCHEMBL31377131 | 0.81 | GBA1 (0.49) | GBA1KDM2BCHRM2CHRM4 | |
| SCHEMBL27584353 | 0.79 | KDM2B (0.52) | KDM2B | |
| SCHEMBL21047314 | 0.77 | KDM2B (0.57) | KDM2B | |
| SCHEMBL20438228 | 0.76 | SMN1; SMN2 (0.42) | SMN1; SMN2CHRM5ADRA2CGBA1ACHE | |
| SCHEMBL10509286 | 0.72 | GBA1 (0.56) | SMN1; SMN2CHRM5ADRA2CGBA1ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009032326-A1 | NEW TETRACYCLINE DERIVATIVES AS ANTIINFECTIVE AGENTS | DR. REDDY'S LABORATORIES LTD. (IN) | 2009-03-12 | — | — | WO | disclosed |