SCHEMBL27564988

SCHEMBL27564988

CCC(=O)CC.CCc1ccccc1O

nearest known ligand 0.55

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
IAPP P10997 3/20 0.55
AKR1B1 P15121 1/20 0.54
HSPA5 P11021 1/20 0.50
GABRA1 P14867 1/20 0.48
GABRB2 P47870 1/20 0.48
TSHR P16473 2/20 0.45
CYP2D6 P10635 1/20 0.45
HIF1A Q16665 1/20 0.45
HTR1A P08908 1/20 0.44
TDP1 Q9NUW8 1/20 0.43
TAAR1 Q96RJ0 1/20 0.43
IDO1 P14902 1/20 0.42
CA12 O43570 1/20 0.42
CA2 P00918 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29402855 0.89
SCHEMBL51108 0.89
Propionic Acid SCHEMBL27286991 0.87 AKR1B1 (0.65) IAPPAKR1B1HSPA5GABRA1GABRB2
Water SCHEMBL27672138 0.86 HSPA5 (0.59) AKR1B1HSPA5GABRA1GABRB2TSHR
SCHEMBL27616243 0.86 TDP1 (0.53) IAPPAKR1B1GABRA1GABRB2TDP1
SCHEMBL27541365 0.86 HSPA5 (0.59) AKR1B1HSPA5GABRA1GABRB2TSHR
SCHEMBL27808385 0.86 HSPA5 (0.59) AKR1B1HSPA5GABRA1GABRB2TSHR
SCHEMBL7392161 0.86 HSPA5 (0.59) AKR1B1HSPA5GABRA1GABRB2TSHR
Ammonia Solution, Strong SCHEMBL267493 0.86 HSPA5 (0.59) AKR1B1HSPA5GABRA1GABRB2TSHR
Propane SCHEMBL27876137 0.86 HSPA5 (0.59) AKR1B1HSPA5GABRA1GABRB2TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1251575-A Oxime ether compounds, their use and intermediates for preparing same SUMITOMO CHEMICAL CO (JP) 2000-04-26 CN disclosed