SCHEMBL27566735

SCHEMBL27566735

OC[CH]C1CCC(O)CC1

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.33
SHBG P04278 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1515344 0.88
SCHEMBL6435554 0.77
SCHEMBL17080534 0.77
SCHEMBL3361649 0.76 SHBG (0.41) TSHRSHBG
SCHEMBL3363724 0.76 SHBG (0.41) TSHRSHBG
SCHEMBL3364455 0.76 SHBG (0.41) TSHRSHBG
SCHEMBL1043089 0.74
SCHEMBL16876944 0.74 TSHR (0.30) TSHRSHBG
SCHEMBL1515009 0.70
SCHEMBL12062579 0.69 TSHR (0.41) TSHRSHBG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1800176-A Heterocyclic sulfonamide inhibitors of beta amyloid production ARQULE (US) 2006-07-12 CN disclosed
CN-1263750-C Heterocyclic sulfonamide inhibitors of beta amyloid production WYETH CORP (US) 2006-07-12 CN disclosed
CN-1503790-A Heterocyclic sulfonamide inhibitors of beta amyloid production 2004-06-09 CN disclosed