Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.45 |
| ▸ | FAAH | O00519 | 3/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | CNR1 | P21554 | 2/20 | 0.42 |
| ▸ | CNR2 | P34972 | 2/20 | 0.42 |
| ▸ | TOP1 | P11387 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.41 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24678433 | 0.90 | ALDH1A1 (0.51) | ALDH1A1MAPK1L3MBTL1EPHX2FAAH | |
| SCHEMBL28192004 | 0.86 | EPHX2 (0.60) | EPHX2FAAHALOX15HSD17B10CNR1 | |
| SCHEMBL28906277 | 0.86 | EPHX2 (0.60) | EPHX2FAAHALOX15HSD17B10CNR1 | |
| SCHEMBL4623962 | 0.86 | EPHX2 (0.60) | EPHX2FAAHALOX15HSD17B10CNR1 | |
| SCHEMBL15537993 | 0.86 | EPHX2 (0.60) | EPHX2FAAHALOX15HSD17B10CNR1 | |
| SCHEMBL29035432 | 0.86 | EPHX2 (0.60) | EPHX2FAAHALOX15HSD17B10CNR1 | |
| SCHEMBL4623958 | 0.86 | EPHX2 (0.60) | EPHX2FAAHALOX15HSD17B10CNR1 | |
| SCHEMBL27674153 | 0.86 | EPHX2 (0.60) | EPHX2FAAHALOX15HSD17B10CNR1 | |
| SCHEMBL27280748 | 0.84 | ALDH1A1 (0.58) | ALDH1A1MAPK1L3MBTL1EPHX2FAAH | |
| SCHEMBL7500149 | 0.84 | EPHX2 (0.62) | ALDH1A1EPHX2FAAHCYP3A4ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1324348-A | TAN-1057 derivatives | BAYER AG (DE) | 2001-11-28 | — | — | CN | disclosed |