Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PI4KA | P42356 | 12/20 | 0.71 |
| ▸ | PI4K2B | Q8TCG2 | 12/20 | 0.71 |
| ▸ | PI4K2A | Q9BTU6 | 12/20 | 0.71 |
| ▸ | PI4KB | Q9UBF8 | 12/20 | 0.71 |
| ▸ | ADORA2A | P29274 | 11/20 | 0.56 |
| ▸ | ADORA1 | P30542 | 8/20 | 0.56 |
| ▸ | ADORA2B | P29275 | 4/20 | 0.51 |
| ▸ | GSK3B | P49841 | 1/20 | 0.49 |
| ▸ | EGFR | P00533 | 1/20 | 0.49 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1233713 | 0.83 | PI4KA (0.69) | PI4KAPI4K2BPI4K2API4KBADORA2A | |
| SCHEMBL5021593 | 0.83 | PI4KA (1.00) | PI4KAPI4K2BPI4K2API4KBADORA2A | |
| SCHEMBL11476962 | 0.80 | PI4KA (0.75) | PI4KAPI4K2BPI4K2API4KBADORA2A | |
| SCHEMBL20049726 | 0.80 | PI4KA (0.75) | PI4KAPI4K2BPI4K2API4KBADORA2A | |
| SCHEMBL22666249 | 0.78 | PI4KA (0.74) | PI4KAPI4K2BPI4K2API4KBADORA2A | |
| SCHEMBL20253540 | 0.78 | PI4KA (0.74) | PI4KAPI4K2BPI4K2API4KBADORA2A | |
| SCHEMBL6699970 | 0.76 | PI4KA (0.59) | PI4KAPI4K2BPI4K2API4KBADORA2A | |
| SCHEMBL1357265 | 0.76 | ADORA2A (0.60) | PI4KAPI4K2BPI4K2API4KBADORA2A | |
| SCHEMBL580610 | 0.75 | ADORA2A (0.64) | PI4KAPI4K2BPI4K2API4KBADORA2A | |
| SCHEMBL21090693 | 0.75 | PI4KA (0.67) | PI4KAPI4K2BPI4K2API4KBADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1398588-A | Application of arecaline hydrobromide as medicine for arrhythmia | XIA GUOJIN (CN) | 2003-02-26 | — | — | CN | disclosed |