Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | FDPS | P14324 | 2/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | SMPD1 | P17405 | 6/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.31 |
| ▸ | CA4 | P22748 | 1/20 | 0.30 |
| ▸ | PGK1 | P00558 | 1/20 | 0.30 |
| ▸ | PGK2 | P07205 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL332472 | 1.00 | — | — | |
| SCHEMBL18394941 | 0.97 | LMNA (0.38) | LMNAFDPSBLMTDP1SMPD1 | |
| SCHEMBL27801260 | 0.97 | LMNA (0.38) | LMNAFDPSBLMTDP1SMPD1 | |
| SCHEMBL5400918 | 0.97 | LMNA (0.38) | LMNAFDPSBLMTDP1SMPD1 | |
| Ammonia Solution, Strong SCHEMBL1310966 | 0.97 | LMNA (0.38) | LMNAFDPSBLMTDP1SMPD1 | |
| Ammonia Solution, Strong SCHEMBL17670033 | 0.97 | LMNA (0.38) | LMNAFDPSBLMTDP1SMPD1 | |
| SCHEMBL17749561 | 0.87 | SMPD1 (0.32) | LMNAFDPSBLMTDP1SMPD1 | |
| SCHEMBL12918830 | 0.83 | — | — | |
| SCHEMBL243552 | 0.80 | LMNA (0.40) | LMNAFDPSBLMTDP1CA2 | |
| SCHEMBL5963785 | 0.80 | LMNA (0.40) | LMNAFDPSBLMTDP1SMPD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105367482-A | N-acylsulfamide apoptosis accelerator | ASTRAZENECA AB | 2016-03-02 | — | — | CN | disclosed |
| CN-103153954-B | N-acylsulfonamide apoptosis promoters | ASTRAZENECA AB (SE) | 2015-11-25 | — | — | CN | disclosed |
| CN-103153954-A | N-acylsulfonamide apoptosis promoters | ASTRAZENECA AB | 2013-06-12 | — | — | CN | disclosed |
| CN-1390234-A | Amine-containing graft polymers, a method for making same, and their use | EXXON CHEMICAL PATENTS INC (US) | 2003-01-08 | — | — | CN | disclosed |