Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.32 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27547821 | 0.86 | P2RX7 (0.33) | KMT2A | |
| SCHEMBL27547826 | 0.84 | DDR1 (0.34) | — | |
| SCHEMBL27577855 | 0.84 | TP53 (0.31) | ALDH1A1 | |
| SCHEMBL27550066 | 0.83 | EED (0.33) | — | |
| SCHEMBL27547825 | 0.83 | KDM4E (0.32) | — | |
| SCHEMBL27567991 | 0.83 | KDM4E (0.32) | — | |
| SCHEMBL27568182 | 0.82 | KMT2A (0.31) | KMT2A | |
| SCHEMBL27680765 | 0.77 | — | — | |
| SCHEMBL27547827 | 0.74 | — | — | |
| SCHEMBL27506696 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1319963-C | Dihydrothiaphenanthrenecarbonylguanidines: composition, process of making, and use as medicament or diagnostic aid | AVENTIS PHARMACEUTICAL GERMANY (DE) | 2007-06-06 | — | — | CN | disclosed |
| CN-1630649-A | Dihydrothiaphenanthrenecarbonylguanidines: composition, process of making, and use as medicament or diagnostic aid | AVENTIS PHARMACEUTICAL GERMANY (DE) | 2005-06-22 | — | — | CN | disclosed |