Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.41 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.41 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.36 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27568202 | 0.83 | KMT2A (0.44) | KMT2AALDH1A1MEN1PRSS1PRSS2 | |
| SCHEMBL16472170 | 0.82 | PRSS1 (0.57) | KMT2AALDH1A1MEN1HPGDPRSS1 | |
| SCHEMBL27517014 | 0.82 | KMT2A (0.45) | KMT2AALDH1A1MEN1PRSS1PRSS2 | |
| SCHEMBL7275147 | 0.81 | KMT2A (0.57) | KMT2AALDH1A1MEN1HPGDPRSS1 | |
| SCHEMBL6957498 | 0.80 | ALDH1A1 (0.49) | KMT2AALDH1A1MEN1HPGDESR1 | |
| SCHEMBL10711104 | 0.80 | KMT2A (0.49) | KMT2AALDH1A1MEN1HPGDMAPK1 | |
| SCHEMBL3781760 | 0.78 | CYP3A4 (0.50) | KMT2APRSS1PRSS2PRSS3ESR1 | |
| SCHEMBL7970809 | 0.78 | HPGD (0.45) | KMT2AALDH1A1MEN1HPGDESR1 | |
| SCHEMBL863991 | 0.78 | MAOB (0.46) | PRSS1FFAR1FFAR4 | |
| SCHEMBL27498672 | 0.77 | F2 (0.48) | KMT2AALDH1A1MEN1SMN1; SMN2EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1391556-A | novel IL-8 receptor antagonists | FOURNIER IND & SANTE (FR) | 2003-01-15 | — | — | CN | disclosed |