Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.40 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.31 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27576138 | 0.91 | PARP1 (0.40) | PARP1CSNK2A1KDM4EHPGDMAPT | |
| SCHEMBL30669533 | 0.71 | CSNK2A1 (0.56) | PARP1CSNK2A1KDM4EHPGDMAPT | |
| SCHEMBL29116821 | 0.71 | CSNK2A1 (0.56) | PARP1CSNK2A1KDM4EHPGDMAPT | |
| SCHEMBL7865622 | 0.70 | HTT (0.47) | MAPTMEN1GAAKMT2ATDP1 | |
| SCHEMBL6816898 | 0.69 | CSNK2A1 (0.50) | PARP1CSNK2A1KDM4EHPGDMAPT | |
| SCHEMBL27528049 | 0.69 | SMN1; SMN2 (0.37) | KDM4EHPGDMAPTMEN1GAA | |
| SCHEMBL27535605 | 0.68 | SMN1; SMN2 (0.39) | PARP1KDM4EMAPTMEN1GAA | |
| SCHEMBL7185410 | 0.66 | MEN1 (0.38) | KDM4EHPGDMAPTMEN1GAA | |
| SCHEMBL27516293 | 0.66 | KDM4E (0.38) | KDM4EHPGDMAPTPOLBGAA | |
| SCHEMBL7171381 | 0.65 | CXCR2 (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1356899-A | IL-8 receptor antagonists | SMITHKLINE BEECHAM CORP (US) | 2002-07-03 | — | — | CN | disclosed |