Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MPL | P40238 | 4/20 | 0.48 |
| ▸ | F2 | P00734 | 3/20 | 0.45 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.45 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.45 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.45 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.43 |
| ▸ | TTR | P02766 | 2/20 | 0.42 |
| ▸ | CTRC | Q99895 | 2/20 | 0.42 |
| ▸ | AURKA | O14965 | 1/20 | 0.41 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.41 |
| ▸ | ATIC | P31939 | 1/20 | 0.40 |
| ▸ | ALPL | P05186 | 1/20 | 0.40 |
| ▸ | ALPI | P09923 | 1/20 | 0.40 |
| ▸ | ALPG | P10696 | 1/20 | 0.40 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | FABP4 | P15090 | 1/20 | 0.39 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1807925 | 0.91 | MPL (0.51) | MPLCTRB1TTRCTRCMCL1 | |
| SCHEMBL11189769 | 0.89 | MPL (0.50) | MPLCTRB1TTRCTRCMCL1 | |
| SCHEMBL27985168 | 0.89 | MPL (0.50) | MPLCTRB1TTRCTRCMCL1 | |
| SCHEMBL9175976 | 0.89 | MPL (0.50) | MPLCTRB1TTRCTRCMCL1 | |
| Pimagedine SCHEMBL27577167 | 0.85 | MPL (0.43) | MPLF2PRSS1PRSS2PRSS3 | |
| Phenol SCHEMBL11600861 | 0.84 | MPL (0.50) | MPLCTRB1TTRCTRCMCL1 | |
| SCHEMBL1806513 | 0.79 | CA2 (0.61) | MPLMCL1ATICALPLALPI | |
| SCHEMBL888245 | 0.79 | MPL (0.49) | MPLTTRAURKAAURKBMCL1 | |
| SCHEMBL9175984 | 0.78 | DUSP5 (0.50) | MPLMCL1ALPLALPIALPG | |
| Potassium Ion SCHEMBL30561037 | 0.78 | PTGS1 (0.49) | MPLF2PRSS1PRSS2PRSS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100392106-C | Production of tanned leather and products suitable therefore | CLARIANT FINANCE BVI LTD (GB) | 2008-06-04 | — | — | CN | disclosed |
| CN-1488003-A | Production of tanned leather and products suitable therefore | �����ﰲ�ز���(BVI)����˾ | 2004-04-07 | — | — | CN | disclosed |