Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | C5AR1 | P21730 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.46 |
| ▸ | PTGER1 | P34995 | 3/20 | 0.44 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.44 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.44 |
| ▸ | PDE4A | P27815 | 2/20 | 0.44 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.44 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.44 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.41 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1446554 | 0.90 | KAT2B (0.44) | C5AR1PTGER1FOLH1PDE4BPDE4A | |
| SCHEMBL7219195 | 0.90 | C5AR1 (0.48) | C5AR1ALDH1A1MEN1KMT2ASGMS2 | |
| SCHEMBL27595601 | 0.82 | CTSV (0.50) | C5AR1ALDH1A1MEN1KMT2ASGMS2 | |
| SCHEMBL4728946 | 0.80 | CTSV (0.57) | FOLH1SRD5A1SRD5A2KDM4E | |
| SCHEMBL3138320 | 0.80 | CTSV (0.57) | FOLH1SRD5A1SRD5A2KDM4E | |
| SCHEMBL7352767 | 0.79 | C5AR1 (0.56) | C5AR1ALDH1A1MEN1KMT2APTGER1 | |
| SCHEMBL12793473 | 0.77 | NPC1 (0.50) | ALDH1A1MEN1KMT2ASGMS2SRD5A1 | |
| SCHEMBL31151927 | 0.77 | CTSV (0.52) | ALDH1A1MEN1KMT2APTGER1FOLH1 | |
| SCHEMBL4220259 | 0.77 | MCL1 (0.54) | ALDH1A1MEN1KMT2APTGER1FOLH1 | |
| SCHEMBL1446522 | 0.76 | PDE4D (0.46) | ALDH1A1PTGER1PDE4BPDE4APDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100404517-C | Bicyclic heterocycles, pharmaceutical compositions containing these compounds, their use and processes for their preparation | BOEHRINGER INGELHEIM PHARMA (DE) | 2008-07-23 | — | — | CN | disclosed |
| CN-1449390-A | Bicyclic heterocycles, pharmaceutical compositions containing these compounds, their use and processes for their preparation | BOEHRINGER INGELHEIM PHARMA (DE) | 2003-10-15 | — | — | CN | disclosed |