Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.38 |
| ▸ | MEN1 | O00255 | 6/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | HCAR3 | P49019 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | ASPH | Q12797 | 1/20 | 0.34 |
| ▸ | KDM8 | Q8N371 | 1/20 | 0.34 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.34 |
| ▸ | AKR1C2 | P52895 | 3/20 | 0.34 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MYC | P01106 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5989837 | 0.89 | IDO1 (0.47) | IDO1KMT2AMEN1CYP1A2CYP2C19 | |
| SCHEMBL27578006 | 0.87 | IDO1 (0.37) | IDO1KMT2AMEN1CYP1A2CYP2C19 | |
| SCHEMBL27557743 | 0.86 | IDO1 (0.41) | IDO1KMT2AMEN1TDP1MAPT | |
| SCHEMBL27577990 | 0.81 | MEN1 (0.44) | IDO1KMT2AMEN1TDP1MAP2K1 | |
| SCHEMBL5991530 | 0.80 | KMT2A (0.44) | IDO1KMT2AMEN1CYP1A2CYP2C19 | |
| SCHEMBL5989631 | 0.79 | MEN1 (0.61) | KMT2AMEN1CYP1A2CYP2C19TDP1 | |
| SCHEMBL5989816 | 0.75 | IDO1 (0.45) | IDO1KMT2AMEN1CYP1A2CYP2C19 | |
| SCHEMBL5989793 | 0.75 | IDO1 (0.46) | IDO1KMT2AMEN1CYP1A2CYP2C19 | |
| SCHEMBL27578023 | 0.75 | MEN1 (0.43) | IDO1KMT2AMEN1TDP1MAP2K1 | |
| SCHEMBL27608158 | 0.74 | MAP2K1 (0.43) | IDO1KMT2AMEN1TDP1MAP2K1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1358094-A | Methods of treating chronic pain with MEK inhibitors | WARNER LAMBERT CO (US) | 2002-07-10 | — | — | CN | disclosed |