Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 1/20 | 0.51 |
| ▸ | CNR2 | P34972 | 3/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 2/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.43 |
| ▸ | PPARD | Q03181 | 1/20 | 0.43 |
| ▸ | PPARA | Q07869 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.43 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.43 |
| ▸ | CNR1 | P21554 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9124454 | 0.86 | CNR2 (0.51) | PDE4BCNR2L3MBTL1ALDH1A1GAA | |
| SCHEMBL9127195 | 0.85 | PDE4B (0.51) | PDE4BCNR2L3MBTL1MAPTALDH1A1 | |
| SCHEMBL10906264 | 0.82 | PPARA (0.44) | CNR2MAPTALDH1A1GAASMN1; SMN2 | |
| SCHEMBL11119371 | 0.81 | PDE4B (0.51) | PDE4BL3MBTL1MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL10907733 | 0.81 | HDAC6 (0.43) | CNR2MAPTALDH1A1GAAMAPK1 | |
| SCHEMBL12238638 | 0.80 | CNR2 (0.50) | CNR2MAPTALDH1A1GAAMAPK1 | |
| SCHEMBL6172845 | 0.80 | KEAP1 (0.55) | CNR2MAPTALDH1A1GAAMAPK1 | |
| SCHEMBL11667468 | 0.79 | CNR2 (0.50) | PDE4BCNR2PPARGKEAP1NFE2L2 | |
| SCHEMBL12238631 | 0.79 | CNR2 (0.47) | CNR2MAPTALDH1A1GAAMAPK1 | |
| SCHEMBL31037871 | 0.78 | SRC (0.48) | CNR2L3MBTL1MAPTALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1348441-A | N-substituted arylsulfonylamino hydroxamic acids | FIBROGEN INC (US) | 2002-05-08 | — | — | CN | disclosed |