Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 4/20 | 0.39 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.38 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 12/20 | 0.38 |
| ▸ | HTR2A | P28223 | 11/20 | 0.38 |
| ▸ | HTR2B | P41595 | 10/20 | 0.38 |
| ▸ | LATS1 | O95835 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27581051 | 1.00 | GSK3B (0.39) | GSK3BROCK1ROCK2HTR2CHTR2A | |
| SCHEMBL20149920 | 0.75 | GSK3B (0.36) | GSK3BROCK1ROCK2HTR2CHTR2A | |
| SCHEMBL5797267 | 0.73 | HTR2C (0.48) | GSK3BROCK1ROCK2HTR2CHTR2A | |
| SCHEMBL16391491 | 0.73 | LATS1 (0.34) | GSK3BROCK1ROCK2HTR2CLATS1 | |
| SCHEMBL16391581 | 0.73 | LATS1 (0.34) | GSK3BROCK1ROCK2HTR2CHTR2B | |
| SCHEMBL17744671 | 0.73 | LATS1 (0.34) | GSK3BROCK1ROCK2HTR2CLATS1 | |
| Hydrochloric Acid SCHEMBL2892940 | 0.72 | KDM4E (0.50) | GSK3BROCK1ROCK2HTR2CHTR2A | |
| Hydrochloric Acid SCHEMBL16235859 | 0.72 | KDM4E (0.50) | GSK3BROCK1ROCK2HTR2CHTR2A | |
| SCHEMBL13931360 | 0.72 | HTR2C (0.53) | HTR2CHTR2AHTR2B | |
| SCHEMBL3682101 | 0.72 | HTR2C (0.60) | GSK3BHTR2CHTR2AHTR2BLATS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1351497-A | Aminopyrimidines as sorbitol dehydrogenase inhibitors | PFIZER PROD INC (US) | 2002-05-29 | — | — | CN | disclosed |