Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 4/20 | 0.36 |
| ▸ | LATS1 | O95835 | 1/20 | 0.35 |
| ▸ | ROCK1 | Q13464 | 4/20 | 0.34 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.34 |
| ▸ | HTR2C | P28335 | 7/20 | 0.34 |
| ▸ | HTR2A | P28223 | 3/20 | 0.33 |
| ▸ | HTR3A | P46098 | 1/20 | 0.33 |
| ▸ | RAD52 | P43351 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27581051 | 0.75 | GSK3B (0.39) | GSK3BLATS1ROCK1ROCK2HTR2C | |
| SCHEMBL27581053 | 0.75 | GSK3B (0.39) | GSK3BLATS1ROCK1ROCK2HTR2C | |
| SCHEMBL26669667 | 0.73 | GSK3B (0.34) | GSK3BLATS1ROCK1ROCK2HTR2C | |
| SCHEMBL16578761 | 0.73 | GSK3B (0.34) | GSK3BLATS1ROCK1ROCK2HTR2C | |
| Hydrochloric Acid SCHEMBL26600152 | 0.72 | RAD52 (0.36) | GSK3BLATS1ROCK1ROCK2HTR2C | |
| SCHEMBL18291384 | 0.69 | HTR2C (0.44) | GSK3BROCK1ROCK2HTR2CHTR2A | |
| SCHEMBL17871510 | 0.69 | MMP2 (0.40) | GSK3BLATS1ROCK1ROCK2HTR2C | |
| SCHEMBL20142347 | 0.68 | HTR2C (0.43) | GSK3BLATS1ROCK1HTR2CHTR2A | |
| SCHEMBL20037535 | 0.68 | HTR2C (0.41) | GSK3BLATS1HTR2CHTR2AKCNH2 | |
| SCHEMBL22489453 | 0.68 | BPTF (0.55) | HTR2CHTR2AHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089499-A1 | PHENYL AMINO PIPERIDINE mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |