Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | CCNC | P24863 | 1/20 | 0.37 |
| ▸ | CDK8 | P49336 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27598671 | 0.91 | POLB (0.41) | POLBKMT2ASLC6A3ALDH1A1LMNA | |
| SCHEMBL5859139 | 0.76 | MAPK1 (0.38) | KMT2ACYP2C9 | |
| SCHEMBL27581096 | 0.76 | KMT2A (0.43) | KMT2AALDH1A1KDM4E | |
| SCHEMBL27598662 | 0.75 | KMT2A (0.40) | POLBKMT2ASLC6A3ALDH1A1KDM4E | |
| SCHEMBL5859939 | 0.74 | DHODH (0.39) | KMT2ACCNCCDK8CYP2C9 | |
| SCHEMBL27581186 | 0.72 | KMT2A (0.40) | POLBKMT2ASLC6A3ALDH1A1CCNC | |
| SCHEMBL5859828 | 0.72 | KCNA5 (0.33) | KMT2ATDP1 | |
| SCHEMBL27581183 | 0.70 | TDP1 (0.33) | ALDH1A1TDP1 | |
| SCHEMBL27544390 | 0.70 | POLB (0.55) | POLBKMT2ASLC6A3ALDH1A1LMNA | |
| SCHEMBL5859135 | 0.67 | ROCK2 (0.41) | ALDH1A1CYP3A4CYP1A2CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1505603-A | Substituted benzoic ac id derivatives exhibiting nf-kappab inhibiting activity | ��һ��������ҩ��ʽ���� | 2004-06-16 | — | — | CN | disclosed |