Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 7/20 | 0.38 |
| ▸ | PRKCA | P17252 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | GSK3A | P49840 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | CDK2 | P24941 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | RGS12 | O14924 | 1/20 | 0.36 |
| ▸ | GMNN | O75496 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CDK1 | P06493 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CDK4 | P11802 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6589113 | 0.89 | CHEK1 (0.44) | GSK3BPRKCAKMT2AGSK3APOLB | |
| SCHEMBL27580859 | 0.88 | GSK3B (0.38) | GSK3BPRKCAGSK3ACDK2MAPK1 | |
| SCHEMBL6588770 | 0.86 | KDM4E (0.41) | GSK3BPRKCAKMT2AGSK3APOLB | |
| SCHEMBL6588767 | 0.85 | GSK3B (0.35) | GSK3BPRKCAKMT2AGSK3APOLB | |
| SCHEMBL6588432 | 0.84 | GSK3B (0.42) | GSK3BCDK2KDM4ECHEK1PLK1 | |
| Trifluoroacetic Acid SCHEMBL6588835 | 0.82 | CHEK1 (0.39) | GSK3BPRKCAKMT2ACDK2KDM4E | |
| SCHEMBL27559927 | 0.82 | GSK3B (0.38) | GSK3BPRKCAKMT2AGSK3APOLB | |
| Trifluoroacetic Acid SCHEMBL6590532 | 0.79 | CDK2 (0.38) | GSK3BKMT2ACDK2CYP1A2CYP3A4 | |
| SCHEMBL6594854 | 0.78 | GSK3B (0.42) | GSK3BPRKCAGSK3ACDK2MAPK1 | |
| SCHEMBL27581115 | 0.77 | HSP90AA1 (0.37) | GSK3BPRKCAHSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1351602-A | Novel Pharmaceutically Active Compounds | ASTRAZENECA AB (SE) | 2002-05-29 | — | — | CN | disclosed |