Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 10/20 | 0.51 |
| ▸ | CHRNA4 | P43681 | 9/20 | 0.51 |
| ▸ | CHRNA3 | P32297 | 7/20 | 0.51 |
| ▸ | CHRNB4 | P30926 | 6/20 | 0.51 |
| ▸ | CHRNA7 | P36544 | 5/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.47 |
| ▸ | CHRNG | P07510 | 1/20 | 0.47 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | CHRND | Q07001 | 1/20 | 0.47 |
| ▸ | CHRNA2 | Q15822 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31637165 | 0.76 | CHRNB2 (0.53) | CHRNB2CHRNA4CHRNA3CHRNB4CHRNA7 | |
| SCHEMBL7193197 | 0.76 | CHRNB2 (0.53) | CHRNB2CHRNA4CHRNA3CHRNB4CHRNA7 | |
| SCHEMBL1747783 | 0.75 | CHRNB2 (0.44) | CHRNB2CHRNA4CHRNA3CHRNB4CHRNA7 | |
| SCHEMBL1747668 | 0.75 | MAP4K1 (0.46) | CHRNB2CHRNA4CHRNA3CHRNB4CHRNA7 | |
| SCHEMBL20401781 | 0.73 | CHRNB2 (0.57) | CHRNB2CHRNA4CHRNA3CHRNB4CHRNA7 | |
| SCHEMBL25330905 | 0.73 | CHRNB2 (0.49) | CHRNB2CHRNA4CHRNA3CHRNB4CHRNA7 | |
| SCHEMBL7999250 | 0.73 | MAPT (0.53) | CHRNB2CHRNA4CHRNA3CHRNB4CHRNA7 | |
| SCHEMBL1481609 | 0.72 | CHRNB2 (0.53) | CHRNB2CHRNA4CHRNA3CHRNB4CHRNA7 | |
| SCHEMBL30847846 | 0.72 | CHRNB2 (0.53) | CHRNB2CHRNA4CHRNA3CHRNB4CHRNA7 | |
| SCHEMBL1001194 | 0.72 | MAPT (0.33) | CHRNB2CHRNA4ALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1392874-A | Cyclic amidine compounds | SUNTORY LTD (JP) | 2003-01-22 | — | — | CN | claimed |