SCHEMBL27585367

SCHEMBL27585367

c1ccc(-c2cc3cccc4c5cccc6cccc(c(c2)c34)c65)cc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.48
MAOA P21397 2/20 0.48
ERBB2 P04626 1/20 0.48
FYN P06241 1/20 0.48
ACHE P22303 1/20 0.48
AHR P35869 1/20 0.48
ALDH1A1 P00352 5/20 0.48
HPGD P15428 4/20 0.48
HSD17B10 Q99714 3/20 0.48
THRB P10828 1/20 0.48
HTR6 P50406 2/20 0.40
TSHR P16473 2/20 0.39
MAPK1 P28482 2/20 0.39
CASP1 P29466 2/20 0.39
HIF1A Q16665 2/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
MET P08581 1/20 0.38
KDM4E B2RXH2 3/20 0.37
MEN1 O00255 3/20 0.37
KMT2A Q03164 3/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3296067 0.89 CYP1A2 (0.43) CYP1A2MAOAERBB2FYNACHE
SCHEMBL13523469 0.87 CYP1A2 (0.38) CYP1A2MAOAERBB2FYNACHE
Biphenyl SCHEMBL2852876 0.87 ALDH1A1 (0.62) CYP1A2MAOAERBB2FYNACHE
SCHEMBL27630929 0.87 ALDH1A1 (0.62) CYP1A2MAOAERBB2FYNACHE
SCHEMBL27786846 0.86 ALDH1A1 (0.44) CYP1A2MAOAERBB2FYNACHE
SCHEMBL24250469 0.84 ALDH1A1 (0.47) CYP1A2MAOAALDH1A1HSD17B10HTR6
Tannin Pyrogallol SCHEMBL23752685 0.84 ALDH1A1 (0.59) CYP1A2MAOAERBB2FYNACHE
SCHEMBL1372254 0.82 CYP1A2 (0.40) CYP1A2MAOAERBB2FYNACHE
SCHEMBL3462089 0.82 ALDH1A1 (0.55) CYP1A2MAOAERBB2FYNACHE
SCHEMBL25112679 0.82 CYP1A2 (0.45) CYP1A2MAOAERBB2FYNACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1386123-A Aryl-substituted poly-p-arylenevinylenes KONINKL PHILIPS ELECTRONICS NV (NL) 2002-12-18 CN disclosed