SCHEMBL27586754

SCHEMBL27586754

COC(C)(C(C)=O)C(C)(O)C(O)C(O)CO

nearest known ligand 0.32

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
PDE4A P27815 1/20 0.31
LMNA P02545 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1425361 1.00 PDE4A (0.31) PDE4ALMNAL3MBTL1TDP1
SCHEMBL27839941 0.83
SCHEMBL4532762 0.74 LMNA (0.36) PDE4ALMNAL3MBTL1TDP1
SCHEMBL28892067 0.74 PDE4A (0.32) PDE4ALMNAL3MBTL1TDP1
SCHEMBL18954089 0.74 PDE4A (0.32) PDE4ALMNAL3MBTL1TDP1
SCHEMBL9120539 0.74 USP2 (0.34) PDE4ALMNA
SCHEMBL10882248 0.72 LMNA (0.32) LMNAL3MBTL1TDP1
SCHEMBL25226372 0.72
SCHEMBL28406761 0.71 LMNA (0.33) PDE4ALMNAL3MBTL1TDP1
SCHEMBL3646782 0.71 LMNA (0.33) PDE4ALMNAL3MBTL1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105682649-A Compositions and methods for reducing overdose 艾萨·欧蒂迪 2016-06-15 CN disclosed
CN-101389619-A Synthetic techniques and intermediates for polyhydroxy dienyl lactones and mimics thereof UNIV PENNSYLVANIA (US) 2009-03-18 CN disclosed
CN-100374154-C Sincalide formulations BRACCO INT BV (NL) 2008-03-12 CN disclosed
CN-1756557-A Sincalide formulations BRACCO INT BV (NL) 2006-04-05 CN disclosed
CN-1541096-A Compounds which mimic chemical and biological properties of discodermolide ��Ϧ�����Ǵ�ѧ���»� 2004-10-27 CN disclosed