Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 2/20 | 0.43 |
| ▸ | TOP1 | P11387 | 4/20 | 0.43 |
| ▸ | HTR1A | P08908 | 3/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 4/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.37 |
| ▸ | CYP2C8 | P10632 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | CYP2B6 | P20813 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.36 |
| ▸ | LTA4H | P09960 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22435151 | 0.87 | AOC3 (0.43) | AOC3TOP1ALOX5 | |
| SCHEMBL23920671 | 0.86 | AOC3 (0.42) | AOC3TOP1HTR1AALOX5CYP3A4 | |
| SCHEMBL31195739 | 0.85 | AOC3 (0.44) | AOC3TOP1HTR1ACYP3A4 | |
| SCHEMBL22571314 | 0.80 | AOC3 (0.45) | AOC3ALOX5CYP1A2 | |
| SCHEMBL14399554 | 0.79 | AOC3 (0.50) | AOC3ALOX5CYP1A2 | |
| SCHEMBL27692331 | 0.79 | AOC3 (0.44) | AOC3TOP1 | |
| SCHEMBL28309046 | 0.78 | SMN1; SMN2 (0.42) | TOP1ALOX5 | |
| SCHEMBL10077163 | 0.78 | TOP1 (0.48) | TOP1HTR1AALOX5CYP3A4CYP2C8 | |
| SCHEMBL9439794 | 0.76 | SMN1; SMN2 (0.40) | TOP1ALOX5 | |
| SCHEMBL23920596 | 0.75 | AOC3 (0.46) | AOC3ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1398182-A | Dual inhibitors of cholestery lester and wax ester synthesis for sebaceous gland disorders | WARNER LAMBERT CO (US) | 2003-02-19 | — | — | CN | disclosed |