Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 3/20 | 0.43 |
| ▸ | TOP1 | P11387 | 4/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.34 |
| ▸ | DHFR | P00374 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.33 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.33 |
| ▸ | PDE1A | P54750 | 1/20 | 0.33 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.33 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | SMAD3 | P84022 | 1/20 | 0.33 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.33 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22571314 | 0.90 | AOC3 (0.45) | AOC3SMN1; SMN2PDE1APDE1BPDE1C | |
| SCHEMBL27587124 | 0.87 | AOC3 (0.43) | AOC3TOP1ALOX5 | |
| SCHEMBL14399554 | 0.86 | AOC3 (0.50) | AOC3SMN1; SMN2PDE1APDE1BPDE1C | |
| SCHEMBL27692331 | 0.82 | AOC3 (0.44) | AOC3TOP1LMNAMAPTKMT2A | |
| SCHEMBL28309046 | 0.81 | SMN1; SMN2 (0.42) | TOP1TSHRMAPTDHFREGFR | |
| SCHEMBL31195739 | 0.79 | AOC3 (0.44) | AOC3TOP1 | |
| SCHEMBL23920671 | 0.76 | AOC3 (0.42) | AOC3TOP1LMNAALOX5 | |
| SCHEMBL23920596 | 0.75 | AOC3 (0.46) | AOC3KMT2ASMN1; SMN2ALOX5TAS1R3 | |
| SCHEMBL22571301 | 0.74 | AOC3 (0.49) | AOC3TSHRLMNAMAPTPDE1A | |
| SCHEMBL22432025 | 0.72 | TOP1 (0.34) | TOP1TSHRDHFREGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11505528-B2 | Inhibitors of microbially induced amyloid | AXIAL THERAPEUTICS, INC. (US) | 2022-11-22 | — | — | US | disclosed |
| US-20200290970-A1 | INHIBITORS OF MICROBIALLY INDUCED AMYLOID | AXIAL BIOTHERAPEUTICS, INC. (US) | 2020-09-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11505528-B2 | Inhibitors of microbially induced amyloid | SNCA, PARK7, PRNP | AOC3 1883/4885TOP1 4602/4885TSHR 4566/4885 |
| US-20200290970-A1 | INHIBITORS OF MICROBIALLY INDUCED AMYLOID | SNCA, PARK7, PRNP | AOC3 1883/4885TOP1 4602/4885TSHR 4566/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.