Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VDR | P11473 | 3/20 | 0.60 |
| ▸ | MAOB | P27338 | 7/20 | 0.32 |
| ▸ | MAOA | P21397 | 4/20 | 0.32 |
| ▸ | PPARD | Q03181 | 1/20 | 0.31 |
| ▸ | PPARA | Q07869 | 1/20 | 0.31 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.31 |
| ▸ | S1PR5 | Q9H228 | 3/20 | 0.31 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.30 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.30 |
| ▸ | CDK7 | P50613 | 1/20 | 0.30 |
| ▸ | JAK3 | P52333 | 1/20 | 0.30 |
| ▸ | TNK2 | Q07912 | 1/20 | 0.30 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.30 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.30 |
| ▸ | STAT3 | P40763 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27577864 | 0.89 | VDR (0.57) | VDRMAOBMAOAPPARDPPARA | |
| SCHEMBL27568037 | 0.87 | VDR (0.46) | VDRPPARDPPARA | |
| SCHEMBL27587224 | 0.87 | VDR (0.46) | VDRMAOB | |
| SCHEMBL27587215 | 0.87 | VDR (0.46) | VDRPPARDPPARAPTGER4 | |
| SCHEMBL6563016 | 0.86 | VDR (0.80) | VDRMAOBMAOAS1PR1S1PR5 | |
| SCHEMBL27587223 | 0.83 | VDR (0.43) | VDRMAOB | |
| SCHEMBL27568006 | 0.83 | VDR (0.45) | VDRMAOB | |
| SCHEMBL27587368 | 0.82 | VDR (0.44) | VDRPPARD | |
| SCHEMBL6564192 | 0.79 | VDR (0.68) | VDRMAOBPPARDS1PR1S1PR5 | |
| SCHEMBL2854911 | 0.79 | VDR (0.88) | VDRMAOBMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1423627-A | Vitamin D analogues | GALDERMA RES & DEV (FR) | 2003-06-11 | — | — | CN | disclosed |