Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 2/20 | 0.67 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.67 |
| ▸ | AURKA | O14965 | 1/20 | 0.67 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.67 |
| ▸ | JAK2 | O60674 | 1/20 | 0.67 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.67 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.67 |
| ▸ | PAK4 | O96013 | 1/20 | 0.67 |
| ▸ | ABL1 | P00519 | 1/20 | 0.67 |
| ▸ | LCK | P06239 | 1/20 | 0.67 |
| ▸ | CSF1R | P07333 | 1/20 | 0.67 |
| ▸ | RET | P07949 | 1/20 | 0.67 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.67 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.67 |
| ▸ | PRKACA | P17612 | 1/20 | 0.67 |
| ▸ | FLT1 | P17948 | 1/20 | 0.67 |
| ▸ | LTK | P29376 | 1/20 | 0.67 |
| ▸ | GRK5 | P34947 | 1/20 | 0.67 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.67 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25273793 | 0.93 | KDR (0.59) | KDRCDK5AURKADAPK3JAK2 | |
| SCHEMBL4917316 | 0.89 | KDR (0.71) | KDRCDK5AURKADAPK3JAK2 | |
| SCHEMBL4923735 | 0.89 | PRMT1 (0.66) | KDRCDK5AURKADAPK3JAK2 | |
| SCHEMBL4922745 | 0.85 | PRMT1 (0.69) | KDRCDK5AURKADAPK3JAK2 | |
| SCHEMBL4912992 | 0.85 | PRMT1 (0.62) | KDRCDK5AURKADAPK3JAK2 | |
| SCHEMBL4922705 | 0.83 | KDR (0.64) | KDRCDK5AURKADAPK3JAK2 | |
| SCHEMBL4922342 | 0.83 | LMNA (0.64) | KDRCDK5AURKADAPK3JAK2 | |
| SCHEMBL4923989 | 0.83 | KDR (0.67) | KDRCDK5AURKADAPK3JAK2 | |
| SCHEMBL4913560 | 0.83 | PRMT1 (0.69) | KDRCDK5AURKADAPK3JAK2 | |
| SCHEMBL4924081 | 0.83 | CDC7 (0.70) | KDRCDK5AURKADAPK3JAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1556808-A | Based on N6Heterocyclic compounds of substituted adenine, process for their preparation, their use for the preparation of medicaments, cosmetic preparations and growth regulators, pharmaceutical preparations, cosmetic preparations and growth regulators containing these compounds | �ݿ˹�����������ʵ��ֲ��ѧ�� | 2004-12-22 | — | — | CN | disclosed |