Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 4/20 | 0.76 |
| ▸ | PIM3 | Q86V86 | 2/20 | 0.47 |
| ▸ | CCNB2 | O95067 | 3/20 | 0.46 |
| ▸ | CDK1 | P06493 | 3/20 | 0.46 |
| ▸ | CCNB1 | P14635 | 3/20 | 0.46 |
| ▸ | CDK5 | Q00535 | 3/20 | 0.46 |
| ▸ | CDK5R1 | Q15078 | 3/20 | 0.46 |
| ▸ | CCNB3 | Q8WWL7 | 3/20 | 0.46 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.46 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.46 |
| ▸ | CDK4 | P11802 | 1/20 | 0.46 |
| ▸ | EIF2AK2 | P19525 | 1/20 | 0.46 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.46 |
| ▸ | CCND1 | P24385 | 1/20 | 0.46 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.46 |
| ▸ | CDK2 | P24941 | 1/20 | 0.46 |
| ▸ | CDK9 | P50750 | 1/20 | 0.46 |
| ▸ | CAMK2B | Q13554 | 1/20 | 0.46 |
| ▸ | CAMK2G | Q13555 | 1/20 | 0.46 |
| ▸ | CAMK2D | Q13557 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2324939 | 0.86 | AR (1.00) | ARPIM3CCNB2CDK1CCNB1 | |
| SCHEMBL27977982 | 0.82 | AR (0.51) | ARPIM3CCNB2CDK1CCNB1 | |
| SCHEMBL29755083 | 0.82 | AR (0.51) | ARPIM3CCNB2CDK1CCNB1 | |
| SCHEMBL11806866 | 0.82 | AR (0.56) | ARCDK5CDK5R1CDK4CCND1 | |
| SCHEMBL20434645 | 0.79 | KIF11 (0.58) | ARPIM3CDK4CCND1CAMK2B | |
| SCHEMBL329557 | 0.77 | AR (0.62) | ARMEN1TP53CYP3A4MAPT | |
| SCHEMBL14716762 | 0.76 | KIF11 (0.68) | ARPIM3CCNB2CDK1CCNB1 | |
| SCHEMBL29963214 | 0.76 | KIF11 (0.68) | ARPIM3CCNB2CDK1CCNB1 | |
| SCHEMBL10868611 | 0.76 | AR (0.61) | ARMEN1TP53CYP3A4MAPT | |
| SCHEMBL28463756 | 0.76 | AR (0.61) | ARMEN1TP53CYP3A4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1423637-A | Novel substituted tricyclic compounds | ASAHI CHEMICAL IND (JP) | 2003-06-11 | — | — | CN | disclosed |