Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR1 | P25024 | 3/20 | 0.71 |
| ▸ | CXCR2 | P25025 | 3/20 | 0.71 |
| ▸ | PPIA | P62937 | 2/20 | 0.65 |
| ▸ | MEN1 | O00255 | 5/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.62 |
| ▸ | MAPT | P10636 | 4/20 | 0.62 |
| ▸ | LMNA | P02545 | 2/20 | 0.62 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.56 |
| ▸ | PPIF | P30405 | 1/20 | 0.55 |
| ▸ | CA12 | O43570 | 1/20 | 0.55 |
| ▸ | CA1 | P00915 | 1/20 | 0.55 |
| ▸ | CA2 | P00918 | 1/20 | 0.55 |
| ▸ | CA9 | Q16790 | 1/20 | 0.55 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.54 |
| ▸ | CTSV | O60911 | 1/20 | 0.54 |
| ▸ | CTSL | P07711 | 1/20 | 0.54 |
| ▸ | NOX1 | Q9Y5S8 | 2/20 | 0.53 |
| ▸ | MAOB | P27338 | 2/20 | 0.53 |
| ▸ | AR | P10275 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5594982 | 0.85 | CXCR2 (0.79) | CXCR1CXCR2PPIAMEN1KMT2A | |
| SCHEMBL5595180 | 0.84 | CXCR2 (1.00) | CXCR1CXCR2MEN1KMT2AMAPT | |
| SCHEMBL31222305 | 0.84 | CXCR2 (1.00) | CXCR1CXCR2MEN1KMT2AMAPT | |
| SCHEMBL7549877 | 0.84 | CXCR1 (0.65) | CXCR1CXCR2MEN1KMT2AMAPT | |
| SCHEMBL7487951 | 0.83 | CXCR1 (0.63) | CXCR1CXCR2PPIAMEN1KMT2A | |
| SCHEMBL5594999 | 0.82 | CXCR2 (0.85) | CXCR1CXCR2MEN1KMT2AMAPT | |
| SCHEMBL5387738 | 0.81 | KCNMA1 (0.58) | CXCR1CXCR2PPIAMEN1KMT2A | |
| SCHEMBL5595009 | 0.81 | CXCR1 (0.84) | CXCR1CXCR2MEN1KMT2AMAPT | |
| SCHEMBL17287914 | 0.81 | CXCR1 (0.70) | CXCR1CXCR2MEN1KMT2AMAPT | |
| SCHEMBL7553576 | 0.78 | CXCR1 (0.74) | CXCR1CXCR2MEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1539816-A | IL-8 receptor antagonists | ʷ��˿�������ȳ�ķ����˾ | 2004-10-27 | — | — | CN | disclosed |