Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | IDO1 | P14902 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | AGXT | P21549 | 1/20 | 0.40 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.40 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MPI | P34949 | 1/20 | 0.40 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27588567 | 0.76 | CYP3A4 (0.50) | ALDH1A1LMNASMN1; SMN2CA12CA1 | |
| SCHEMBL27606385 | 0.76 | HRH3 (0.39) | TAAR1CA12CA1CA2CA7 | |
| SCHEMBL1425001 | 0.73 | LTA4H (0.81) | LTA4HALDH1A1LMNACYP2D6ATM | |
| SCHEMBL25986524 | 0.73 | LTA4H (0.81) | LTA4HALDH1A1LMNACYP2D6ATM | |
| SCHEMBL27884 | 0.73 | LTA4H (0.81) | LTA4HALDH1A1LMNACYP2D6ATM | |
| SCHEMBL27543797 | 0.73 | CYP17A1 (0.38) | ALDH1A1CYP2D6SMN1; SMN2HPGDPOLB | |
| Ammonia Solution, Strong SCHEMBL20919857 | 0.71 | LTA4H (0.77) | LTA4HALDH1A1LMNACYP2D6ATM | |
| SCHEMBL27606510 | 0.68 | TP53 (0.46) | ALDH1A1SMN1; SMN2HPGDKDM4ECA12 | |
| SCHEMBL24321390 | 0.68 | LTA4H (0.71) | LTA4HALDH1A1LMNACYP2D6ATM | |
| SCHEMBL22451382 | 0.68 | LTA4H (0.71) | LTA4HALDH1A1LMNACYP2D6ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1553900-A | Acylsemicarbazides as cyclin dependent kinase inhibitors useful as anti-cancer and anti-proliferative agents | ��ʱ��ʩ����ҩ��˾ | 2004-12-08 | — | — | CN | disclosed |