SCHEMBL27592147

SCHEMBL27592147

CC(C(N)=O)C1CN(c2ccc(-c3cnc(N)nc3)c(F)c2)C(=O)O1

nearest known ligand 0.51

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
CALML3 P27482 6/20 0.51
CYP2C19 P33261 2/20 0.50
CYP3A4 P08684 1/20 0.50
MAOA P21397 10/20 0.49
MAOB P27338 1/20 0.47
CYP2C9 P11712 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27592144 1.00 CALML3 (0.51) CALML3CYP2C19CYP3A4MAOAMAOB
SCHEMBL27573559 0.91 CYP2C19 (0.51) CALML3CYP2C19CYP3A4MAOAMAOB
SCHEMBL27573562 0.91 CYP2C19 (0.51) CALML3CYP2C19CYP3A4MAOAMAOB
SCHEMBL27573564 0.90 MAOA (0.48) CALML3CYP2C19CYP3A4MAOAMAOB
SCHEMBL27573568 0.90 MAOA (0.48) CALML3CYP2C19CYP3A4MAOAMAOB
SCHEMBL27592112 0.90 CALML3 (0.53) CALML3CYP2C19CYP3A4MAOAMAOB
SCHEMBL27592107 0.88 MAOA (0.49) CALML3CYP2C19CYP3A4MAOAMAOB
SCHEMBL27592108 0.88 MAOA (0.49) CALML3CYP2C19CYP3A4MAOAMAOB
SCHEMBL6644686 0.87 CYP2C19 (0.48) CALML3CYP2C19CYP3A4MAOAMAOB
SCHEMBL27592471 0.86 CALML3 (0.52) CALML3CYP2C19CYP3A4MAOAMAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1433413-A Oxazolidinone derivatives and process for their preparation DONG A PHARM CO LTD (KR) 2003-07-30 CN claimed
CN-1433413-A Oxazolidinone derivatives and process for their preparation DONG A PHARM CO LTD (KR) 2003-07-30 CN disclosed