Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR4 | O00206 | 5/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.38 |
| ▸ | MAP2K7 | O14733 | 1/20 | 0.38 |
| ▸ | MAP2K4 | P45985 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 3/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | LIMK2 | P53671 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27985645 | 0.88 | TLR4 (0.46) | TLR4NPC1RAB9AKMT2AMEN1 | |
| SCHEMBL27883083 | 0.86 | TLR4 (0.41) | TLR4RAB9ASMN1; SMN2MAPTPOLB | |
| SCHEMBL27573674 | 0.86 | TLR4 (0.48) | TLR4NPC1RAB9AKMT2AMEN1 | |
| SCHEMBL27592261 | 0.85 | TLR4 (0.48) | TLR4NPC1RAB9AKMT2ATHRB | |
| SCHEMBL27985935 | 0.84 | TLR4 (0.48) | TLR4NPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL871804 | 0.84 | TLR4 (0.69) | TLR4NPC1RAB9AKMT2AMEN1 | |
| SCHEMBL27985969 | 0.84 | TLR4 (0.47) | TLR4NPC1RAB9AKMT2AMEN1 | |
| SCHEMBL872918 | 0.81 | TLR4 (0.58) | TLR4NPC1RAB9AGAASMN1; SMN2 | |
| SCHEMBL27985964 | 0.81 | TLR4 (0.55) | TLR4NPC1RAB9AGAAPOLB | |
| SCHEMBL28159349 | 0.81 | TLR4 (0.58) | TLR4NPC1RAB9AGAASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102821763-B | Compound for inhibiting peripheral nerve disorder induced by anticancer agent | 武田药品工业株式会社 | 2017-09-22 | — | — | CN | disclosed |
| CN-101212986-B | Stable emulsified composition | TAKEDA PHARMACEUTICAL | 2015-01-14 | — | — | CN | disclosed |
| CN-102821763-A | Compound for inhibiting peripheral nerve disorder induced by anticancer agent | TAKEDA PHARMACEUTICAL | 2012-12-12 | — | — | CN | disclosed |
| CN-102670503-A | Stable emulsion composition | TAKEDA PHARMACEUTICAL | 2012-09-19 | — | — | CN | disclosed |
| CN-1416341-B | Stable emulsion compositions | TAKEDA CHEMICAL INDUSTRIES LTD | 2010-05-05 | — | — | CN | disclosed |
| CN-101212986-A | stable emulsified composition | TAKEDA PHARMACEUTICAL (JP) | 2008-07-02 | — | — | CN | disclosed |
| CN-1416341-A | Stable emulsion compsns | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2003-05-07 | — | — | CN | disclosed |