Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR4 | O00206 | 5/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | FABP4 | P15090 | 2/20 | 0.37 |
| ▸ | FABP5 | Q01469 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.35 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | GFER | P55789 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27592261 | 0.86 | TLR4 (0.48) | TLR4NPC1RAB9AMAPTGLA | |
| SCHEMBL27592250 | 0.84 | TLR4 (0.48) | TLR4SMN1; SMN2NPC1RAB9AMAPT | |
| SCHEMBL27573716 | 0.84 | TLR4 (0.48) | TLR4SMN1; SMN2NPC1RAB9AALDH1A1 | |
| SCHEMBL27985645 | 0.84 | TLR4 (0.46) | TLR4SMN1; SMN2NPC1RAB9A | |
| SCHEMBL871345 | 0.83 | TLR4 (0.71) | TLR4MAPTTP53ALDH1A1LMNA | |
| SCHEMBL27985962 | 0.82 | TLR4 (0.53) | TLR4SMN1; SMN2NPC1RAB9ATP53 | |
| SCHEMBL27985969 | 0.82 | TLR4 (0.47) | TLR4NPC1RAB9AALDH1A1 | |
| SCHEMBL27573674 | 0.82 | TLR4 (0.48) | TLR4SMN1; SMN2NPC1RAB9AMAPT | |
| SCHEMBL27985964 | 0.82 | TLR4 (0.55) | TLR4NPC1RAB9ATP53ALDH1A1 | |
| SCHEMBL27883083 | 0.82 | TLR4 (0.41) | TLR4SMN1; SMN2RAB9AMAPTTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102821763-B | Compound for inhibiting peripheral nerve disorder induced by anticancer agent | 武田药品工业株式会社 | 2017-09-22 | — | — | CN | disclosed |
| CN-101212986-B | Stable emulsified composition | TAKEDA PHARMACEUTICAL | 2015-01-14 | — | — | CN | disclosed |