Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 13/20 | 0.56 |
| ▸ | HTR2C | P28335 | 10/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27611419 | 0.91 | MCHR1 (0.53) | MCHR1HTR2CHDAC1 | |
| SCHEMBL5648818 | 0.87 | MCHR1 (0.74) | MCHR1HTR2CHDAC1 | |
| SCHEMBL27593333 | 0.85 | MCHR1 (0.76) | MCHR1HTR2CMAPTSMN1; SMN2RXFP1 | |
| SCHEMBL27611417 | 0.84 | MCHR1 (0.65) | MCHR1HTR2C | |
| SCHEMBL27593224 | 0.82 | MCHR1 (0.55) | MCHR1HTR2CMAPTLMNASMN1; SMN2 | |
| SCHEMBL27611493 | 0.82 | HTR2C (0.58) | MCHR1HTR2CMAPTLMNASMN1; SMN2 | |
| SCHEMBL27611409 | 0.81 | MCHR1 (0.60) | MCHR1HTR2CMAPTHDAC1 | |
| SCHEMBL27611455 | 0.80 | MCHR1 (0.56) | MCHR1HTR2CSMN1; SMN2HDAC1 | |
| SCHEMBL5647112 | 0.80 | MCHR1 (0.77) | MCHR1HTR2CHDAC1 | |
| SCHEMBL5651130 | 0.79 | MCHR1 (0.83) | MCHR1HTR2CHDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1585751-A | Quinoline compound | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2005-02-23 | — | — | CN | disclosed |