Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 13/20 | 0.60 |
| ▸ | HTR2C | P28335 | 9/20 | 0.60 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.42 |
| ▸ | SMO | Q99835 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5647206 | 0.88 | MCHR1 (0.79) | MCHR1HTR2CHDAC1 | |
| SCHEMBL27611493 | 0.86 | HTR2C (0.58) | MCHR1HTR2CHDAC1MAPTFAAH | |
| SCHEMBL27611455 | 0.84 | MCHR1 (0.56) | MCHR1HTR2CHDAC1NPC1RAB9A | |
| SCHEMBL27593224 | 0.82 | MCHR1 (0.55) | MCHR1HTR2CHDAC1MAPT | |
| SCHEMBL27593277 | 0.81 | MCHR1 (0.56) | MCHR1HTR2CHDAC1MAPT | |
| SCHEMBL27611419 | 0.81 | MCHR1 (0.53) | MCHR1HTR2CHDAC1 | |
| SCHEMBL27611545 | 0.80 | MCHR1 (0.56) | MCHR1HTR2CHDAC1FAAH | |
| SCHEMBL5645505 | 0.77 | MCHR1 (0.86) | MCHR1HTR2CHDAC1 | |
| SCHEMBL5644815 | 0.76 | MCHR1 (0.80) | MCHR1HTR2C | |
| SCHEMBL5647406 | 0.75 | MCHR1 (1.00) | MCHR1HTR2CHDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1585751-A | Quinoline compound | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2005-02-23 | — | — | CN | disclosed |