Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A3 | P43003 | 1/20 | 0.41 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.41 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.41 |
| ▸ | NOS1 | P29475 | 2/20 | 0.38 |
| ▸ | NOS3 | P29474 | 1/20 | 0.38 |
| ▸ | NOS2 | P35228 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.37 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16392545 | 0.92 | SLC1A3 (0.41) | SLC1A3SLC1A2SLC1A1NOS1NOS3 | |
| SCHEMBL3240752 | 0.84 | NOS1 (0.41) | SLC1A3SLC1A2SLC1A1NOS1NOS3 | |
| Hydrochloric Acid SCHEMBL28773975 | 0.82 | NOS1 (0.41) | SLC1A3SLC1A2SLC1A1NOS1NOS3 | |
| SCHEMBL28062530 | 0.79 | NOS1 (0.46) | SLC1A3SLC1A2SLC1A1NOS1NOS3 | |
| Hydrochloric Acid SCHEMBL8848963 | 0.77 | NOS1 (0.45) | SLC1A3SLC1A2SLC1A1NOS1NOS3 | |
| SCHEMBL318908 | 0.76 | NOS1 (0.43) | SLC1A3SLC1A2SLC1A1NOS1NOS3 | |
| SCHEMBL318907 | 0.76 | NOS1 (0.43) | SLC1A3SLC1A2SLC1A1NOS1NOS3 | |
| SCHEMBL12549336 | 0.76 | NOS1 (0.43) | SLC1A3SLC1A2SLC1A1NOS1NOS3 | |
| SCHEMBL17775437 | 0.76 | SLC1A3 (0.39) | SLC1A3SLC1A2SLC1A1NOS1NOS3 | |
| SCHEMBL311538 | 0.76 | SLC1A3 (0.39) | SLC1A3SLC1A2SLC1A1NOS1NOS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1437581-A | Glucagon antagonists/inverse agonists | NOVO NORDISK AS (DK) | 2003-08-20 | — | — | CN | disclosed |