Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.30 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27594327 | 0.81 | KDM4E (0.51) | ALOX5HSP90AA1 | |
| SCHEMBL27594332 | 0.81 | HDAC3 (0.40) | — | |
| SCHEMBL27612911 | 0.78 | HDAC1 (0.40) | ALOX5 | |
| SCHEMBL27594326 | 0.77 | CYP3A4 (0.35) | — | |
| SCHEMBL27594333 | 0.77 | WRN (0.32) | — | |
| SCHEMBL27613073 | 0.74 | CYP2A6 (0.47) | — | |
| SCHEMBL27613063 | 0.74 | HDAC4 (0.43) | — | |
| SCHEMBL4008739 | 0.70 | MAPT (0.48) | HSP90AA1 | |
| SCHEMBL18331590 | 0.66 | HSP90AA1 (0.41) | HSP90AA1 | |
| SCHEMBL6852263 | 0.65 | KDM4E (0.36) | HSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1585775-A | 6-O-acyl ketolide derivatives of erythromycine useful as antibacterials | ORTHO MCNEIL PHARM INC (US) | 2005-02-23 | — | — | CN | disclosed |