Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27594327 | 0.85 | KDM4E (0.51) | HDAC1ALOX5KDM4ENPC1GLA | |
| SCHEMBL27594332 | 0.78 | HDAC3 (0.40) | HDAC1KDM4EMAPT | |
| SCHEMBL27594201 | 0.78 | ALOX5 (0.30) | ALOX5 | |
| SCHEMBL27613073 | 0.78 | CYP2A6 (0.47) | HDAC1 | |
| SCHEMBL19227845 | 0.74 | HDAC1 (0.47) | HDAC1ALOX5KDM4ENPC1GLA | |
| SCHEMBL27594333 | 0.74 | WRN (0.32) | — | |
| SCHEMBL27612907 | 0.71 | — | — | |
| SCHEMBL27612793 | 0.69 | HDAC4 (0.40) | NPC1RAB9A | |
| SCHEMBL27612769 | 0.65 | HDAC1 (0.45) | HDAC1KDM4ENPC1GLAMAPT | |
| SCHEMBL20267150 | 0.64 | HDAC1 (0.47) | HDAC1KDM4ENPC1GLAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1585775-A | 6-O-acyl ketolide derivatives of erythromycine useful as antibacterials | ORTHO MCNEIL PHARM INC (US) | 2005-02-23 | — | — | CN | disclosed |