Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 5/20 | 0.68 |
| ▸ | SLC2A1 | P11166 | 11/20 | 0.63 |
| ▸ | FAAH | O00519 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4276476 | 1.00 | KCNH2 (0.68) | KCNH2SLC2A1FAAHMEN1KMT2A | |
| SCHEMBL4269202 | 0.88 | KCNH2 (0.65) | KCNH2SLC2A1 | |
| SCHEMBL7017868 | 0.88 | KCNH2 (0.65) | KCNH2SLC2A1 | |
| SCHEMBL27579662 | 0.86 | KCNH2 (0.65) | KCNH2SLC2A1 | |
| SCHEMBL4272906 | 0.86 | KCNH2 (0.65) | KCNH2SLC2A1 | |
| SCHEMBL5775396 | 0.85 | KCNH2 (0.49) | KCNH2SLC2A1FAAH | |
| SCHEMBL4276780 | 0.85 | SLC2A1 (0.65) | KCNH2SLC2A1 | |
| SCHEMBL3770941 | 0.85 | KCNH2 (0.60) | KCNH2SLC2A1MEN1KMT2A | |
| SCHEMBL4276818 | 0.84 | KCNH2 (0.66) | KCNH2SLC2A1 | |
| SCHEMBL5304487 | 0.84 | KCNH2 (0.83) | KCNH2SLC2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1452619-A | Aminopiperidine quinolines and their azaisosteric analogues with antibacterial activity | SMITHKLINE BEECHAM PLC (GB) | 2003-10-29 | — | — | CN | disclosed |