Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 4/20 | 0.49 |
| ▸ | SLC2A1 | P11166 | 10/20 | 0.48 |
| ▸ | FAAH | O00519 | 2/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | TACR1 | P25103 | 1/20 | 0.40 |
| ▸ | TACR3 | P29371 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.40 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5772116 | 0.86 | SLC2A1 (0.48) | KCNH2SLC2A1SIGMAR1HTR1ADRD2 | |
| SCHEMBL4276476 | 0.85 | KCNH2 (0.68) | KCNH2SLC2A1FAAH | |
| SCHEMBL27595294 | 0.85 | KCNH2 (0.68) | KCNH2SLC2A1FAAH | |
| SCHEMBL5773652 | 0.84 | SLC2A1 (0.47) | KCNH2SLC2A1SIGMAR1DRD2DRD3 | |
| SCHEMBL5775045 | 0.83 | KCNH2 (0.52) | KCNH2SLC2A1SIGMAR1DRD2DRD3 | |
| SCHEMBL5772802 | 0.83 | SLC2A1 (0.48) | KCNH2SLC2A1SIGMAR1DRD2 | |
| SCHEMBL5777366 | 0.83 | LMNA (0.47) | KCNH2SLC2A1SIGMAR1DRD2DRD3 | |
| SCHEMBL5778699 | 0.83 | SLC2A1 (0.58) | KCNH2SLC2A1SIGMAR1HTR1ADRD2 | |
| SCHEMBL5777778 | 0.83 | SLC2A1 (0.47) | KCNH2SLC2A1SIGMAR1HTR1ADRD2 | |
| SCHEMBL5258710 | 0.82 | KCNH2 (0.45) | KCNH2SLC2A1SIGMAR1HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1305308-B1 | AMINOPIPERIDINE QUINOLINES AND THEIR AZAISOSTERIC ANALOGUES WITH ANTIBACTERIAL ACTIVITY | SMITHKLINE BEECHAM PLC (GB) | 2006-12-20 | — | — | EP | claimed |