Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | P4HTM | Q9NXG6 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CCR1 | P32246 | 1/20 | 0.43 |
| ▸ | CCR5 | P51681 | 1/20 | 0.43 |
| ▸ | CCR8 | P51685 | 1/20 | 0.43 |
| ▸ | METAP1 | P53582 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | DOHH | Q9BU89 | 1/20 | 0.43 |
| ▸ | NCF1 | P14598 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | CES2 | O00748 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Quinoxaline SCHEMBL27549902 | 0.90 | ALDH1A1 (0.52) | ALDH1A1KDM4EPOLBLMNAP4HTM | |
| Quinoxaline SCHEMBL5315 | 0.90 | ALDH1A1 (0.58) | ALDH1A1KDM4EPOLBLMNAP4HTM | |
| Quinoxaline SCHEMBL29355228 | 0.90 | ALDH1A1 (0.58) | ALDH1A1KDM4EPOLBLMNAP4HTM | |
| Quinoxaline SCHEMBL6928518 | 0.90 | ALDH1A1 (0.58) | ALDH1A1KDM4EPOLBLMNAP4HTM | |
| Quinoxaline SCHEMBL30320908 | 0.90 | ALDH1A1 (0.58) | ALDH1A1KDM4EPOLBLMNAP4HTM | |
| Quinoxaline SCHEMBL27924506 | 0.88 | ALDH1A1 (0.50) | ALDH1A1KDM4EPOLBLMNAP4HTM | |
| Quinoxaline SCHEMBL4292166 | 0.88 | ALDH1A1 (0.50) | ALDH1A1KDM4EPOLBLMNAP4HTM | |
| Quinoxaline SCHEMBL5358841 | 0.87 | ALDH1A1 (0.55) | ALDH1A1KDM4EPOLBLMNAP4HTM | |
| Quinoxaline SCHEMBL4000710 | 0.87 | ALDH1A1 (0.55) | ALDH1A1KDM4EPOLBLMNAP4HTM | |
| Quinoxaline SCHEMBL19877228 | 0.87 | ALDH1A1 (0.55) | ALDH1A1KDM4EPOLBLMNAP4HTM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1609105-A | 1-hydroxymethyl imidazo [1, 2-alpha ] quinoxaline compound and application thereof | INST OF TOXIC PHARMACOLOGY ACA (CN) | 2005-04-27 | — | — | CN | claimed |
| CN-100386326-C | 1-hydroxymethyl imidazo [1, 2-a ] quinoxaline compound and application thereof | INST OF TOXIC PHARMACOLOGY ACA (CN) | 2008-05-07 | — | — | CN | disclosed |
| CN-1609105-A | 1-hydroxymethyl imidazo [1, 2-alpha ] quinoxaline compound and application thereof | INST OF TOXIC PHARMACOLOGY ACA (CN) | 2005-04-27 | — | — | CN | disclosed |