Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP5 | Q01469 | 3/20 | 0.39 |
| ▸ | FABP7 | O15540 | 2/20 | 0.39 |
| ▸ | GRM2 | Q14416 | 5/20 | 0.38 |
| ▸ | GRM3 | Q14832 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | GRM6 | O15303 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4600775 | 0.86 | FABP5 (0.42) | FABP5FABP7GRM2GRM3KMT2A | |
| SCHEMBL4601214 | 0.86 | FABP5 (0.38) | FABP5FABP7GRM2GRM3KMT2A | |
| SCHEMBL4601435 | 0.83 | FABP5 (0.42) | FABP5FABP7GRM2GRM3KMT2A | |
| SCHEMBL27596048 | 0.83 | EPHX2 (0.38) | FABP5FABP7GRM2GRM3KMT2A | |
| SCHEMBL4601160 | 0.82 | FABP5 (0.39) | FABP5FABP7GRM2GRM3KMT2A | |
| SCHEMBL4600307 | 0.81 | FABP5 (0.39) | FABP5FABP7GRM2GRM3KMT2A | |
| SCHEMBL4600355 | 0.80 | EPHX2 (0.38) | FABP5FABP7GRM2GRM3KMT2A | |
| SCHEMBL4601923 | 0.79 | FABP5 (0.40) | FABP5FABP7GRM2EPHX2 | |
| SCHEMBL2190862 | 0.76 | CASP1 (0.41) | FABP5FABP7GRM2GRM3KMT2A | |
| SCHEMBL28864147 | 0.73 | EPHX2 (0.44) | FABP5FABP7KMT2AEPHX2CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100491396-C | Selective cyclic peptides | HOFFMANN LA ROCHE (CH) | 2009-05-27 | — | — | CN | disclosed |
| CN-1451017-A | Selective cyclic peptides | HOFFMANN LA ROCHE (CH) | 2003-10-22 | — | — | CN | disclosed |