Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACLY | P53396 | 1/20 | 0.42 |
| ▸ | ACACB | O00763 | 1/20 | 0.41 |
| ▸ | ACACA | Q13085 | 1/20 | 0.41 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.36 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 8/20 | 0.34 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.33 |
| ▸ | TTR | P02766 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | CISD1 | Q9NZ45 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27578128 | 0.98 | ACLY (0.45) | ACLYACACBACACACYP4F2CYP4A11 | |
| SCHEMBL6691583 | 0.93 | CYP4F2 (0.40) | ACLYACACBACACACYP4F2CYP4A11 | |
| SCHEMBL6692896 | 0.92 | CYP4F2 (0.42) | ACLYACACBACACACYP4F2CYP4A11 | |
| SCHEMBL6504900 | 0.88 | ACLY (0.52) | ACLYACACBACACAPPARATBXAS1 | |
| SCHEMBL6505133 | 0.86 | CYP4F2 (0.36) | CYP4F2CYP4A11 | |
| SCHEMBL6507160 | 0.86 | ACLY (0.55) | ACLYACACBACACACYP4F2CYP4A11 | |
| SCHEMBL6502656 | 0.83 | CYP4F2 (0.33) | CYP4F2CYP4A11 | |
| SCHEMBL6708509 | 0.82 | ACLY (0.48) | ACLYACACBACACAPPARATBXAS1 | |
| SCHEMBL27596160 | 0.82 | ACACB (0.39) | ACLYACACBACACACYP4F2CYP4A11 | |
| SCHEMBL6503462 | 0.81 | ACLY (0.47) | ACLYACACBACACAPPARATBXAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1479721-A | Sulfoxide and bis-sulfoxide compounds and compositions for cholesterol therapy and related applications | ͨ��ҽ�ƹ�˾ | 2004-03-03 | — | — | CN | claimed |