Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | APEX1 | P27695 | 1/20 | 0.45 |
| ▸ | CCR8 | P51685 | 1/20 | 0.45 |
| ▸ | LPAR1 | Q92633 | 4/20 | 0.44 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.43 |
| ▸ | PLG | P00747 | 1/20 | 0.42 |
| ▸ | PLAU | P00749 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.41 |
| ▸ | F7 | P08709 | 1/20 | 0.41 |
| ▸ | F3 | P13726 | 1/20 | 0.41 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.41 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.41 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.41 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.40 |
| ▸ | BRS3 | P32247 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27581050 | 0.90 | PDE10A (0.41) | KDM4EHTTAPEX1CCR8PDE10A | |
| SCHEMBL6098146 | 0.86 | KDM4E (0.48) | KDM4EPOLBHTTAPEX1LPAR1 | |
| SCHEMBL6095164 | 0.86 | KDM4E (0.60) | KDM4EPOLBAPEX1LPAR1LPAR5 | |
| SCHEMBL27579891 | 0.84 | PTGER1 (0.50) | HTTAPEX1MEN1KMT2APTGER1 | |
| SCHEMBL6097784 | 0.80 | HPGD (0.41) | KDM4EPOLBRAB9AMEN1KMT2A | |
| SCHEMBL5859872 | 0.79 | MCL1 (0.53) | KDM4EHTTPTGER1 | |
| SCHEMBL6095093 | 0.78 | KDM4E (0.47) | KDM4EPOLBRAB9AMEN1KMT2A | |
| SCHEMBL27578074 | 0.78 | PTGER1 (0.50) | APEX1PTGER1 | |
| SCHEMBL28746733 | 0.77 | LMNA (0.48) | HTTRAB9A | |
| SCHEMBL5731416 | 0.77 | MRGPRX4 (0.50) | RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1460097-A | NF-kB inhibitor containing substituted benzoic acid derivative as active ingredient | DAIICHI SUNTORY SEIYAKU CO LTD (JP) | 2003-12-03 | — | — | CN | disclosed |