Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | CTNNB1 | P35222 | 2/20 | 0.39 |
| ▸ | WNT3A | P56704 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5563859 | 0.86 | PIK3CG (0.47) | KDM4ENPSR1RXFP1CTNNB1WNT3A | |
| SCHEMBL5563864 | 0.85 | KDM4E (0.38) | KDM4ENPSR1RXFP1CTNNB1WNT3A | |
| Hydrochloric Acid SCHEMBL5569140 | 0.84 | KDM4E (0.38) | KDM4ENPSR1RXFP1CTNNB1WNT3A | |
| SCHEMBL5569139 | 0.81 | SMN1; SMN2 (0.46) | MAPTNPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL5567784 | 0.79 | ALDH1A1 (0.46) | KDM4ENPSR1SMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL5568757 | 0.79 | KMT2A (0.47) | KDM4EMAPTSMN1; SMN2ALDH1A1HTT | |
| SCHEMBL5564379 | 0.79 | NPY5R (0.44) | — | |
| SCHEMBL5569297 | 0.78 | BRD4 (0.44) | — | |
| SCHEMBL14421685 | 0.78 | NPY5R (0.55) | NPSR1HTTTP53 | |
| SCHEMBL5567835 | 0.77 | GAA (0.47) | KDM4EMAPTNPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100363362-C | Thiazole derivatives as NPY receptor antagonists | HOFFMANN LA ROCHE (CH) | 2008-01-23 | — | — | CN | disclosed |
| CN-1639158-A | Thiazole derivatives as NPY receptor antagonists | HOFFMANN LA ROCHE (CH) | 2005-07-13 | — | — | CN | disclosed |