Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHR | P35869 | 1/20 | 0.48 |
| ▸ | CNR2 | P34972 | 2/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 2/20 | 0.45 |
| ▸ | CA2 | P00918 | 2/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | KIF11 | P52732 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.44 |
| ▸ | KDM1A | O60341 | 1/20 | 0.43 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.43 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.43 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.43 |
| ▸ | CES2 | O00748 | 1/20 | 0.43 |
| ▸ | CES1 | P23141 | 1/20 | 0.43 |
| ▸ | FLT1 | P17948 | 1/20 | 0.43 |
| ▸ | FLT4 | P35916 | 1/20 | 0.43 |
| ▸ | KDR | P35968 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28777340 | 0.87 | CYP19A1 (0.55) | AHRCYP19A1KIF11P2RX3CES2 | |
| SCHEMBL196588 | 0.87 | CYP19A1 (0.55) | AHRCYP19A1KIF11P2RX3CES2 | |
| Chloromethane SCHEMBL27654434 | 0.85 | CYP19A1 (0.53) | AHRCNR2CYP19A1KIF11P2RX3 | |
| Water SCHEMBL28260933 | 0.85 | CYP19A1 (0.53) | AHRCYP19A1KIF11P2RX3CES2 | |
| SCHEMBL27896762 | 0.85 | CYP19A1 (0.53) | AHRCYP19A1KIF11P2RX3CES2 | |
| Hydrogen Sulfide SCHEMBL28292229 | 0.85 | CYP19A1 (0.53) | AHRCYP19A1KIF11P2RX3CES2 | |
| Phosphine SCHEMBL28854143 | 0.85 | CYP19A1 (0.53) | AHRCYP19A1KIF11P2RX3CES2 | |
| Water SCHEMBL28855946 | 0.85 | CYP19A1 (0.53) | AHRCYP19A1KIF11P2RX3CES2 | |
| SCHEMBL6743839 | 0.85 | CNR2 (0.51) | AHRCNR2CYP19A1CA1CA2 | |
| Carbon Monoxide SCHEMBL10627238 | 0.83 | CYP19A1 (0.48) | AHRCNR2CYP19A1MAPTTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109608369-A | Sulphonyl ester group anthraquinone derivatives and its preparation method and application | 广西大学 | 2019-04-12 | — | — | CN | claimed |
| CN-109608369-A | Sulphonyl ester group anthraquinone derivatives and its preparation method and application | 广西大学 | 2019-04-12 | — | — | CN | disclosed |
| CN-104822267-B | The inhibitor and its application method that hepatitis b virus covalence closed cyclic DNA is formed | 巴鲁克·S·布伦博格研究所 | 2018-01-23 | — | — | CN | disclosed |
| CN-102336689-A | Preparation and refining method of 4-Cl-(trifluoromethyl) benzene sulfonyl chloride | JUNKAI TIANJIN CHEMICAL CO LTD | 2012-02-01 | — | — | CN | disclosed |
| CN-102336689-A | Preparation and refining method of 4-Cl-(trifluoromethyl) benzene sulfonyl chloride | JUNKAI TIANJIN CHEMICAL CO LTD | 2012-02-01 | — | — | CN | disclosed |
| CN-101027286-B | Indazolone derivatives as 11b-HSD1 inhibitors | HOFFMANN LA ROCHE | 2011-05-25 | — | — | CN | disclosed |
| CN-102036961-A | Pyridine and pyrazine compounds as PI3K inhibitors | NOVARTIS AG | 2011-04-27 | — | — | CN | disclosed |
| CN-101035762-B | Alkil-pyridines as 11-beta inhibitors for diabetes | HOFFMANN LA ROCHE | 2010-09-29 | — | — | CN | disclosed |
| CN-101765591-A | Pyrimidine derivatives useful for the treatment of inflammatory or allergic conditions | NOVARTIS AG | 2010-06-30 | — | — | CN | disclosed |
| CN-100589803-C | Aryl-pyridine derivatives | HOFFMANN LA ROCHE | 2010-02-17 | — | — | CN | disclosed |
| CN-100422179-C | 2-amino-5-benzoylthiazole npy antagonists | HOFFMANN LA ROCHE (CH) | 2008-10-01 | — | — | CN | disclosed |
| CN-100363362-C | Thiazole derivatives as NPY receptor antagonists | HOFFMANN LA ROCHE (CH) | 2008-01-23 | — | — | CN | disclosed |
| CN-101068804-A | Bissulfonamide compounds as agonists of GalR1, compositions, and methods of use | TRANSTECH PHARMA INC (US) | 2007-11-07 | — | — | CN | disclosed |
| CN-101035762-A | Alkil-pyridines as 11-beta inhibitors for diabetes | HOFFMANN LA ROCHE (CH) | 2007-09-12 | — | — | CN | disclosed |
| CN-101027286-A | Indazolone derivatives as 11 b-HSD 1 inhibitors | HOFFMANN LA ROCHE (CH) | 2007-08-29 | — | — | CN | disclosed |
| CN-1988905-A | Aryl-pyridine derivatives | HOFFMANN LA ROCHE (CH) | 2007-06-27 | — | — | CN | disclosed |
| CN-1852907-A | 2-amino-5-benzoylthiazole npy antagonists | HOFFMANN LA ROCHE (CH) | 2006-10-25 | — | — | CN | disclosed |
| CN-1751037-A | Sulfonamide derivatives as PPAR modulators | LILLY CO ELI (US) | 2006-03-22 | — | — | CN | disclosed |
| CN-1639158-A | Thiazole derivatives as NPY receptor antagonists | HOFFMANN LA ROCHE (CH) | 2005-07-13 | — | — | CN | disclosed |
| CN-1549714-A | Aminoisoxazole derivatives active as kinase inhibitors | — | 2004-11-24 | — | — | CN | disclosed |