Hydrogen Sulfide

Hydrogen Sulfide

SCHEMBL28292229

FC(F)(F)c1ccc(Cl)cc1.S

nearest known ligand 0.53

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP19A1 P11511 4/20 0.53
AHR P35869 1/20 0.50
TSHR P16473 2/20 0.48
ALDH1A1 P00352 1/20 0.48
LMNA P02545 1/20 0.47
CYP2A6 P11509 1/20 0.47
KIF11 P52732 4/20 0.46
MEN1 O00255 1/20 0.46
KMT2A Q03164 1/20 0.46
MAPK1 P28482 1/20 0.46
HIF1A Q16665 1/20 0.46
P2RX3 P56373 1/20 0.44
KCNH2 Q12809 1/20 0.44
TMEM97 Q5BJF2 1/20 0.44
CES2 O00748 1/20 0.44
CES1 P23141 1/20 0.44
ORAI1 Q96D31 1/20 0.44
ORAI2 Q96SN7 1/20 0.44
ORAI3 Q9BRQ5 1/20 0.44
TRPV6 Q9H1D0 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL196588 0.97 CYP19A1 (0.55) CYP19A1AHRTSHRALDH1A1LMNA
SCHEMBL28777340 0.97 CYP19A1 (0.55) CYP19A1AHRTSHRALDH1A1LMNA
Chloromethane SCHEMBL27654434 0.94 CYP19A1 (0.53) CYP19A1AHRTSHRALDH1A1LMNA
SCHEMBL27896762 0.94 CYP19A1 (0.53) CYP19A1AHRTSHRALDH1A1LMNA
Water SCHEMBL28855946 0.94 CYP19A1 (0.53) CYP19A1AHRTSHRALDH1A1LMNA
Phosphine SCHEMBL28854143 0.94 CYP19A1 (0.53) CYP19A1AHRTSHRALDH1A1LMNA
Water SCHEMBL28260933 0.94 CYP19A1 (0.53) CYP19A1AHRTSHRALDH1A1LMNA
SCHEMBL8876935 0.89 KIF11 (0.61) CYP19A1AHRKIF11
SCHEMBL16626263 0.89 CYP19A1 (0.50) CYP19A1AHRTSHRALDH1A1LMNA
Carbon Monoxide SCHEMBL10627238 0.87 CYP19A1 (0.48) CYP19A1AHRTSHRALDH1A1P2RX3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109608369-A Sulphonyl ester group anthraquinone derivatives and its preparation method and application 广西大学 2019-04-12 CN disclosed