Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LSS | P48449 | 15/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | UTS2R | Q9UKP6 | 2/20 | 0.34 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27596324 | 1.00 | LSS (0.40) | LSSKDM4ELMNANPC1HPGD | |
| SCHEMBL7208349 | 1.00 | LSS (0.40) | LSSKDM4ELMNANPC1HPGD | |
| SCHEMBL27596322 | 1.00 | LSS (0.40) | LSSKDM4ELMNANPC1HPGD | |
| SCHEMBL27578406 | 0.99 | LSS (0.39) | LSSKDM4ELMNANPC1HPGD | |
| SCHEMBL27578407 | 0.99 | LSS (0.39) | LSSKDM4ELMNANPC1HPGD | |
| SCHEMBL27596254 | 0.91 | LSS (0.39) | LSSLMNAMCHR1 | |
| SCHEMBL27596237 | 0.91 | L3MBTL1 (0.40) | LSSKDM4ELMNANPC1MCHR1 | |
| SCHEMBL27596265 | 0.91 | LSS (0.49) | LSSLMNAMCHR1 | |
| SCHEMBL27596449 | 0.91 | LSS (0.49) | LSSLMNAMCHR1 | |
| SCHEMBL27596450 | 0.91 | LSS (0.49) | LSSLMNAMCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100455566-C | Novel derivatives of aminocyclohexane | HOFFMANN LA ROCHE (CH) | 2009-01-28 | — | — | CN | disclosed |
| CN-1468214-A | Novel derivatives of aminocyclohexane | - | 2004-01-14 | — | — | CN | disclosed |