Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LSS | P48449 | 2/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.31 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27581069 | 0.86 | LSS (0.36) | LSSSIGMAR1 | |
| SCHEMBL27596433 | 0.81 | SIGMAR1 (0.40) | SIGMAR1 | |
| SCHEMBL4798361 | 0.78 | LSS (0.33) | LSSSIGMAR1PIK3CD | |
| SCHEMBL4798372 | 0.78 | LSS (0.33) | LSSSIGMAR1PIK3CD | |
| SCHEMBL4803717 | 0.77 | EPHX2 (0.32) | LSS | |
| SCHEMBL4803724 | 0.77 | EPHX2 (0.32) | LSS | |
| SCHEMBL4800948 | 0.76 | CHRM2 (0.34) | LSSPIK3CD | |
| SCHEMBL4800954 | 0.76 | LSS (0.32) | LSSPIK3CD | |
| SCHEMBL4800963 | 0.76 | LSS (0.32) | LSSPIK3CD | |
| SCHEMBL4800942 | 0.76 | CHRM2 (0.34) | LSSPIK3CD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100455566-C | Novel derivatives of aminocyclohexane | HOFFMANN LA ROCHE (CH) | 2009-01-28 | — | — | CN | disclosed |
| CN-1468214-A | Novel derivatives of aminocyclohexane | - | 2004-01-14 | — | — | CN | disclosed |