SCHEMBL27596757

SCHEMBL27596757

Cln1cnc2ncnc-2c1

nearest known ligand 0.35

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL276721 0.73 LTA4H (0.35) LTA4H
SCHEMBL27606838 0.73 LTA4H (0.35) LTA4H
SCHEMBL2005839 0.70 LTA4H (0.33) LTA4H
SCHEMBL26155647 0.68 LTA4H (0.33) LTA4H
SCHEMBL27575444 0.68 LTA4H (0.44) LTA4H
SCHEMBL2005840 0.68 LTA4H (0.33) LTA4H
SCHEMBL28235029 0.67 LTA4H (0.35) LTA4H
SCHEMBL28182726 0.65 CDK5 (0.36) LTA4H
SCHEMBL28231217 0.62 KDM5A (0.32)
SCHEMBL21274238 0.56

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113453707-A RNA for malaria vaccine 库瑞瓦格股份公司 2021-09-28 CN disclosed
CN-110312528-A Pharmaceutical compositions and methods of treatment for genetic diseases resulting from splicing abnormalities 国立大学法人京都大学 2019-10-08 CN disclosed
CN-108872428-A A kind of adenine is in relation to the efficient liquid phase chromatographic analysis detection method of substance and application 湖北丽益医药科技有限公司 2018-11-23 CN disclosed
CN-107206002-A Prevention or treatment of uric acid or gout disease 上海珊顿医药科技有限公司 2017-09-26 CN disclosed
CN-1617871-A Purine derivatives as purinergic receptor antagonists VERNALIS RES LTD (GB) 2005-05-18 CN disclosed