⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL27643707 | 0.98 | TSHR (0.32) | — | |
| Hydrochloric Acid SCHEMBL27665005 | 0.79 | TSHR (0.34) | — | |
| SCHEMBL27571933 | 0.79 | USP2 (0.37) | — | |
| Hydrochloric Acid SCHEMBL27599189 | 0.79 | TSHR (0.34) | — | |
| SCHEMBL28007476 | 0.71 | — | — | |
| SCHEMBL28218588 | 0.71 | — | — | |
| SCHEMBL28332133 | 0.65 | — | — | |
| SCHEMBL4196209 | 0.64 | — | — | |
| SCHEMBL3588715 | 0.62 | MAPK1 (0.35) | — | |
| SCHEMBL27348052 | 0.62 | TSHR (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111601810-A | Inhibitors of indoleamine 2, 3-dioxygenase and/or tryptophan 2, 3-dioxygenase | 爱杜西亚药品有限公司 | 2020-08-28 | — | — | CN | disclosed |
| CN-110997682-A | Inhibitors of indoleamine 2, 3-dioxygenase and/or tryptophan 2, 3-dioxygenase | 爱杜西亚药品有限公司 | 2020-04-10 | — | — | CN | disclosed |
| CN-108024992-A | Aryl, Heteroaryl and Heterocyclic Compounds for the Treatment of Medical Disorders | 艾其林医药公司 | 2018-05-11 | — | — | CN | disclosed |
| CN-104350059-B | There is the thiazolopyridin ketone of weeding and insecticidal activity | 拜耳知识产权有限责任公司 | 2016-12-07 | — | — | CN | disclosed |
| CN-105612162-A | Thiazolopyrimidinones as modulators of NMDA receptor activity | HOFFMANN LA ROCHE | 2016-05-25 | — | — | CN | disclosed |
| CN-105439977-A | Preparation methods for acotiamide and hydrochloride thereof | GUANGZHOU REGENEX CORP | 2016-03-30 | — | — | CN | disclosed |
| CN-103189376-B | There is ketone group sultam and the diketo pyridine of weeding activity | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2016-02-24 | — | — | CN | disclosed |
| CN-103068814-B | Anthranilic acid derivative | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2015-11-25 | — | — | CN | disclosed |
| CN-105051029-A | Thiazolecarboxamide and picolinamide compounds useful as PIM kinase inhibitors | INCYTE CORP | 2015-11-11 | — | — | CN | disclosed |
| CN-104892544-A | Improved acotiamide intermediate preparation method | BEIJING HOPE INTERNAT PHARMACEUTICAL TECHNOLOGY DEV CO LTD | 2015-09-09 | — | — | CN | disclosed |
| CN-101959882-A | Imidazole carbonyl compound | DAIICHI SANKYO CO LTD | 2011-01-26 | — | — | CN | disclosed |
| CN-101558066-A | Pyrrole derivatives with antibacterial activity | ASTRAZENECA AB (SE) | 2009-10-14 | — | — | CN | disclosed |
| CN-101541801-A | Fused heterocyclic derivative and use thereof | TAKEDA PHARMACEUTICAL (JP) | 2009-09-23 | — | — | CN | disclosed |
| CN-101389627-A | Pyrrolopyridines, pyrrolopyrimidines and pyrroloazepines with antibacterial action | ASTRAZENECA AB (SE) | 2009-03-18 | — | — | CN | disclosed |
| CN-101277946-A | Heterocyclylamide-substituted thiazoles, pyrroles and thiophenes | BAYER HEALTHCARE AG (DE) | 2008-10-01 | — | — | CN | disclosed |
| CN-101048418-A | PI 3-kinase | BOEHRINGER INGELHEIM INT (DE) | 2007-10-03 | — | — | CN | disclosed |
| CN-1886376-A | Pyridine compounds as dipeptidyl dipeptidase-IV inhibitors | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2006-12-27 | — | — | CN | disclosed |
| CN-1832934-A | Benzoxazepine-based compound | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2006-09-13 | — | — | CN | disclosed |
| CN-1636563-A | Thiazole derivatives | AVON PROD INC (US) | 2005-07-13 | — | — | CN | disclosed |
| CN-1478084-A | Compounds useful in treatment of inflammatory diseases | — | 2004-02-25 | — | — | CN | disclosed |