⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16504608 | 0.88 | CYP1A2 (0.34) | — | |
| SCHEMBL1601359 | 0.78 | USP2 (0.42) | — | |
| SCHEMBL310712 | 0.75 | — | — | |
| SCHEMBL1380254 | 0.74 | — | — | |
| SCHEMBL6754852 | 0.72 | SMN1; SMN2 (0.47) | — | |
| SCHEMBL1101400 | 0.72 | — | — | |
| SCHEMBL31470928 | 0.71 | — | — | |
| SCHEMBL7831444 | 0.70 | — | — | |
| Hydrochloric Acid SCHEMBL29471655 | 0.70 | — | — | |
| SCHEMBL4062373 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116249697-A | Bicycloheptane pyrrolidine orexin receptor agonists | 默沙东有限责任公司 | 2023-06-09 | — | — | CN | claimed |
| CN-116249697-A | Bicycloheptane pyrrolidine orexin receptor agonists | 默沙东有限责任公司 | 2023-06-09 | — | — | CN | disclosed |
| US-10113049-B2 | Thermoplastic resin composition | NIPPON NYUKAZAI CO., LTD. (JP) | 2018-10-30 | — | — | US | disclosed |
| CN-104159977-B | Thermoplastic resin composition | 日本乳化剂株式会社 | 2017-09-12 | — | — | CN | disclosed |
| US-20150329698-A1 | THERMOPLASTIC RESIN COMPOSITION | NIPPON NYUKAZAI CO., LTD. (JP) | 2015-11-19 | — | — | US | disclosed |
| CN-104159977-A | Thermoplastic resin composition | NIPPON NYUKAZAI CO LTD | 2014-11-19 | — | — | CN | disclosed |
| US-8642642-B2 | Heterocyclic arylsulphones suitable for treating disorders that respond to modulation of the serotonin 5HT6 receptor | ABBOTT LABORATORIES (US) | 2014-02-04 | — | — | US | disclosed |
| US-20090306175-A1 | HETEROCYCLIC ARYLSULPHONES SUITABLE FOR TREATING DISORDERS THAT RESPOND TO MODULATION OF THE SEROTONIN 5HT6 RECEPTOR | ABBOTT GMBH & CO. KG (DE) | 2009-12-10 | — | — | US | disclosed |
| CN-101421234-A | Is suitable for treating p-hydroxytryptamine 5HT6Heterocyclic aryl sulfones of receptor-modulated responsive disorders | ABBOTT GMBH (DE) | 2009-04-29 | — | — | CN | disclosed |
| EP-2029528-A1 | HETEROCYCLIC ARYLSULPHONES SUITABLE FOR TREATING DISORDERS THAT RESPOND TO MODULATION OF THE SEROTONIN 5HT6 RECEPTOR | Abbott GmbH & Co. KG (DE) | 2009-03-04 | — | — | EP | disclosed |
| WO-2007118899-A1 | HETEROCYCLIC ARYLSULPHONES SUITABLE FOR TREATING DISORDERS THAT RESPOND TO MODULATION OF THE SEROTONIN 5HT6 RECEPTOR | ABBOTT GMBH & CO. KG (DE) | 2007-10-25 | — | — | WO | disclosed |
| WO-2002102175-A1 | BAKE TYPE AROMATISING COMPOSITIONS | SOCIETE DES PRODUITS NESTLE S.A. (CH) | 2002-12-27 | — | — | WO | disclosed |